STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HS3ST2Sulfotransferase; Belongs to the sulfotransferase 1 family. (367 aa)    
Predicted Functional Partners:
HS2ST1
Uncharacterized protein.
   
  
 0.692
EXT2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.587
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.499
CCN5
Cellular communication network factor 5.
      
 0.487
DKK2
Dickkopf WNT signaling pathway inhibitor 2.
      
 0.461
HS6ST1
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.433
SFRP2
Secreted frizzled related protein 2.
      
 0.414
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.413
GPC6
Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.411
GPC4
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.411
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.