Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
SRSF12Serine and arginine rich splicing factor 12. (241 aa)    
Predicted Functional Partners:
TRA2A
Transformer 2 alpha homolog.
   
 0.955
SRSF1
Uncharacterized protein.
   
 0.922
SRSF5
Serine and arginine rich splicing factor 5.
   
 0.865
SRSF6
Serine and arginine rich splicing factor 6.
   
 0.855
SRSF4
Serine and arginine rich splicing factor 4.
   
 0.855
SRSF10
Serine and arginine rich splicing factor 10.
   
 0.843
SRSF7
Serine and arginine rich splicing factor 7.
   
 0.787
TRA2B
Transformer 2 beta homolog.
   
 0.777
CLK2
CDC like kinase 2; Belongs to the protein kinase superfamily.
   
 
 0.767
EIF4A3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 0.765
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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