Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC57Uncharacterized protein. (248 aa)    
Predicted Functional Partners:
C5orf30
Chromosome 5 open reading frame 30.
    
   0.782
LUM
Lumican.
  
     0.519
OMD
Osteomodulin.
  
     0.518
CHAD
Chondroadherin.
  
    0.510
CDHR5
Cadherin related family member 5.
     
 0.508
DNAJC17
DnaJ heat shock protein family (Hsp40) member C17.
   
  
 0.504
DCN
Decorin; May affect the rate of fibrils formation.
  
     0.503
IVD
Isovaleryl-CoA dehydrogenase.
      
 0.492
ME2
Malic enzyme.
   
  
 0.483
ZFYVE19
Zinc finger FYVE-type containing 19.
    
 0.482
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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