Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OAS12'-5'-oligoadenylate synthetase 1. (342 aa)    
Predicted Functional Partners:
OAS3
2'-5'-oligoadenylate synthetase 3.
     
  0.762
OAS2
2'-5'-oligoadenylate synthetase 2.
     
  0.762
RNASEL
Uncharacterized protein.
   
 
 0.684
DHX58
DExH-box helicase 58.
   
  
 0.624
ISG15
ISG15 ubiquitin like modifier.
   
  
 0.598
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.589
POLR3K
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
      
 0.578
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
 
 0.571
PARP9
Poly(ADP-ribose) polymerase family member 9.
   
 
 0.571
EVC2
EvC ciliary complex subunit 2.
      
 0.559
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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