STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK3Non-specific serine/threonine protein kinase. (559 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.989
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.976
NCK1
Cytoplasmic protein.
    
 0.970
RAC2
Rac family small GTPase 2.
   
 0.969
NCK2
Cytoplasmic protein.
    
 0.967
ITSN2
Intersectin 2.
    
 0.953
G3U095_LOXAF
Uncharacterized protein.
    
 0.953
LIMK2
LIM domain kinase 2.
    
0.950
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.937
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.934
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.