Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECE1Endothelin converting enzyme 1. (773 aa)    
Predicted Functional Partners:
EDN1
Endothelin 1.
     
 0.845
MMP14
Matrix metallopeptidase 14.
      
 0.700
TSR1
Bms1-type G domain-containing protein.
      
 0.692
EDN3
Uncharacterized protein.
    
 0.595
ECEL1
Endothelin converting enzyme like 1.
    
   0.569
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.506
FREM1
FRAS1 related extracellular matrix 1.
     
  0.461
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
      
 0.414
EDNRA
Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.
      
 0.409
ACE
Angiotensin-converting enzyme.
     
 0.400
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.