STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRKTyrosine-protein kinase. (516 aa)    
Predicted Functional Partners:
G3T7Q2_LOXAF
Uncharacterized protein.
   
  
 0.945
KIAA1328
Uncharacterized protein.
   
    0.737
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.642
G3TRR6_LOXAF
Uncharacterized protein.
    
 0.642
SH2D1A
SH2 domain containing 1A.
  
 0.625
CSK
Tyrosine-protein kinase.
  
0.605
MATK
Tyrosine-protein kinase.
  
0.605
BCAR1
BCAR1 scaffold protein, Cas family member.
   
 0.583
CD4
CD4 molecule.
   
 0.567
STAP2
Signal transducing adaptor family member 2.
    
 0.549
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.