STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAP1Adenylyl cyclase-associated protein; Belongs to the CAP family. (451 aa)    
Predicted Functional Partners:
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.963
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
   0.927
WDR1
WD repeat domain 1.
   
 
 0.826
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
    
   0.806
TWF1
Twinfilin actin binding protein 1.
   
 
 0.795
TWF2
Twinfilin actin binding protein 2.
   
 
 0.795
BCL7C
BAF chromatin remodeling complex subunit BCL7C.
    
   0.793
PFN4
Profilin; Belongs to the profilin family.
   
 0.778
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.717
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.696
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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