STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1GProtein phosphatase, Mg2+/Mn2+ dependent 1G. (544 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.726
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 0.626
SF3A2
Splicing factor 3a subunit 2.
   
  
 0.609
SIRT7
Sirtuin 7.
    
 
 0.538
PPIL4
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 0.536
PPP6C
Serine/threonine-protein phosphatase.
    
 
 0.523
MMGT1
Membrane magnesium transporter 1.
      
 0.516
THRAP3
Thyroid hormone receptor associated protein 3.
   
 
 0.494
SAC3D1
SAC3 domain containing 1.
      
 0.478
SNRPG
Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
      
 0.475
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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