STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLA2G6Phospholipase A2 group VI. (808 aa)    
Predicted Functional Partners:
CYP2U1
Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.
     
 0.918
ALOX12
Arachidonate 12-lipoxygenase, 12S type.
   
 
 0.909
ALOX5
Arachidonate 5-lipoxygenase.
   
 
 0.908
ALOX15B
Arachidonate 15-lipoxygenase type B.
   
 
 0.904
FADS2
Fatty acid desaturase 2.
     
 0.904
ALOX12B
Arachidonate 12-lipoxygenase, 12R type.
   
 
 0.904
GNAQ
G protein subunit alpha q.
     
 0.902
PEMT
Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
     
 0.902
ENPP6
Ectonucleotide pyrophosphatase/phosphodiesterase 6.
     
 0.902
TMEM86B
Transmembrane protein 86B.
     
 0.902
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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