Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUL5Cullin 5; Belongs to the cullin family. (775 aa)    
Predicted Functional Partners:
ELOB
Elongin B.
    
 0.999
RNF7
Ring finger protein 7.
    
 0.999
ELOC
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.999
RBX1
Ring-box 1.
    
 0.998
SOCS2
Suppressor of cytokine signaling 2.
   
 0.985
ASB9
Ankyrin repeat and SOCS box containing 9.
    
 0.980
SPSB3
SplA/ryanodine receptor domain and SOCS box containing 3.
    
 0.970
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.969
G3SWC6_LOXAF
Uncharacterized protein.
    
 
 0.961
SOCS4
Suppressor of cytokine signaling 4.
   
 0.952
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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