STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCGGlucagon. (178 aa)    
Predicted Functional Partners:
GLP1R
Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.947
GCGR
Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.946
GIPR
Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.918
GLP2R
Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family.
   
 0.901
GHRL
Ghrelin and obestatin prepropeptide.
   
 
 0.867
ADCYAP1R1
ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.
    
 0.850
VIPR2
Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family.
    
 0.842
GPR119
G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family.
     
 0.838
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.826
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
     
 0.819
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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