STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHCR77-dehydrocholesterol reductase. (475 aa)    
Predicted Functional Partners:
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.990
DHCR24
24-dehydrocholesterol reductase.
 
 
 0.981
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.925
SOAT1
O-acyltransferase.
    
 0.914
SOAT2
O-acyltransferase.
    
 0.914
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.911
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 0.907
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
 0.904
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 
 0.903
CEL
Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family.
   
 
 0.901
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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