Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIDO1Death inducer-obliterator 1. (2144 aa)    
Predicted Functional Partners:
WDR82
WD repeat domain 82.
   
 0.887
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
   
 0.871
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.864
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.793
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 0.766
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
   
 0.766
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
      
 0.737
EEF2K
Eukaryotic elongation factor 2 kinase.
   
  
 0.699
HCFC2
Host cell factor C2.
   
 0.584
HCFC1
Host cell factor C1.
   
 0.584
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.