STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G2E3G2/M-phase specific E3 ubiquitin protein ligase. (718 aa)    
Predicted Functional Partners:
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
 
    
 0.724
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.636
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.613
EED
Embryonic ectoderm development.
   
 0.607
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.584
GAS2L3
Growth arrest specific 2 like 3.
   
  
 0.559
ANKRD46
Ankyrin repeat domain 46.
    
 0.557
DLGAP5
DLG associated protein 5.
   
  
 0.530
CDCA2
Cell division cycle associated 2.
   
  
 0.516
CKAP5
Cytoskeleton associated protein 5.
      
 0.516
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.