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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INSCINSC spindle orientation adaptor protein. (579 aa)    
Predicted Functional Partners:
GPSM2
G protein signaling modulator 2.
    
 
 0.901
SEC61G
SEC61 translocon gamma subunit.
   
 
 0.633
TH
Tyrosine hydroxylase.
      
 0.575
TLN1
Talin 1.
    
 0.562
TLNRD1
Talin rod domain containing 1.
    
 0.562
TLN2
Talin 2.
    
 0.562
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 0.543
PARD6A
Par-6 family cell polarity regulator alpha.
      
 0.533
GPSM1
G protein signaling modulator 1.
   
 
 0.503
NUMA1
Nuclear mitotic apparatus protein 1.
   
 
 0.466
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.