STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC8DnaJ heat shock protein family (Hsp40) member C8. (253 aa)    
Predicted Functional Partners:
HSPB9
Heat shock protein family B (small) member 9; Belongs to the small heat shock protein (HSP20) family.
      
 0.584
DNAJC18
DnaJ heat shock protein family (Hsp40) member C18.
    
 
0.526
EIF3L
Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]
      
 0.519
SF3A2
Splicing factor 3a subunit 2.
    
   0.519
PPP1R8
Protein phosphatase 1 regulatory subunit 8.
   
 
 0.517
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
    
 
 0.457
DHX9
DExH-box helicase 9.
   
  0.456
SRRT
Serrate, RNA effector molecule.
   
 
  0.452
DNAJC25
J domain-containing protein.
    
 
 0.449
DNAJC9
DnaJ heat shock protein family (Hsp40) member C9.
    
 
 0.448
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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