STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP3Poly [ADP-ribose] polymerase. (532 aa)    
Predicted Functional Partners:
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 0.975
PARP2
Poly [ADP-ribose] polymerase.
  
 
0.954
PARP4
Poly [ADP-ribose] polymerase.
     
 0.949
PARG
Poly(ADP-ribose) glycohydrolase.
    
 0.923
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 0.901
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.901
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.901
G3TVZ6_LOXAF
Uncharacterized protein.
     
 0.880
G3U1F5_LOXAF
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  0.770
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.706
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.