STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SREBF2Sterol regulatory element binding transcription factor 2. (1109 aa)    
Predicted Functional Partners:
SCAP
SREBF chaperone.
    
 0.961
KPNB1
Karyopherin subunit beta 1.
    
 0.948
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
 0.862
MBTPS1
Membrane bound transcription factor peptidase, site 1.
    
 0.859
CREBBP
CREB binding protein.
    
 0.856
SREBF1
Sterol regulatory element binding transcription factor 1.
   
 0.851
LPIN1
Lipin 1.
    
 0.843
PPARGC1B
PPARG coactivator 1 beta.
    
 0.843
NPC1
NPC intracellular cholesterol transporter 1.
    
 0.833
LDLR
Low density lipoprotein receptor.
   
 
 0.827
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.