STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC42Uncharacterized protein. (147 aa)    
Predicted Functional Partners:
WASL
WASP like actin nucleation promoting factor.
   
 0.997
WAS
WASP actin nucleation promoting factor.
   
 0.997
PAK2
Non-specific serine/threonine protein kinase.
   
 0.996
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.995
PARD6A
Par-6 family cell polarity regulator alpha.
    
 0.985
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.984
PAK6
Non-specific serine/threonine protein kinase.
   
 0.983
ARHGAP1
Rho GTPase activating protein 1.
    
 0.982
IQGAP3
IQ motif containing GTPase activating protein 3.
   
 0.981
IQGAP1
IQ motif containing GTPase activating protein 1.
   
 0.980
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.