STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (890 aa)    
Predicted Functional Partners:
RSPO1
R-spondin 1.
   
 0.994
RSPO2
R-spondin 2.
   
 0.993
RSPO3
R-spondin 3.
   
 0.976
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
  
0.965
RSPO4
R-spondin 4.
   
 0.961
ZNRF3
Zinc and ring finger 3.
    
 0.945
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
  
0.927
RNF43
RING-type domain-containing protein.
    
 0.920
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.690
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.690
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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