SLC25A28 protein (Loxodonta africana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SLC25A28

Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa)

Predicted Functional Partners:

NARS2

0.899

METTL1

0.719

ABCB10

0.697

ARIH1

0.673

FXN

0.624

ISCU

0.616

ABCB7

0.509

RRP9

0.489

MRS2

0.489

MRPL4

0.488

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB10	ABCB7	ENSLAFP00000018464	ENSLAFP00000007382	ATP binding cassette subfamily B member 10.	ATP binding cassette subfamily B member 7.	0.598
ABCB10	SLC25A28	ENSLAFP00000018464	ENSLAFP00000004877	ATP binding cassette subfamily B member 10.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.697
ABCB7	ABCB10	ENSLAFP00000007382	ENSLAFP00000018464	ATP binding cassette subfamily B member 7.	ATP binding cassette subfamily B member 10.	0.598
ABCB7	FXN	ENSLAFP00000007382	ENSLAFP00000008060	ATP binding cassette subfamily B member 7.	Frataxin.	0.723
ABCB7	ISCU	ENSLAFP00000007382	ENSLAFP00000006033	ATP binding cassette subfamily B member 7.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.723
ABCB7	SLC25A28	ENSLAFP00000007382	ENSLAFP00000004877	ATP binding cassette subfamily B member 7.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.509
ARIH1	SLC25A28	ENSLAFP00000004625	ENSLAFP00000004877	RBR-type E3 ubiquitin transferase.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.673
FXN	ABCB7	ENSLAFP00000008060	ENSLAFP00000007382	Frataxin.	ATP binding cassette subfamily B member 7.	0.723
FXN	ISCU	ENSLAFP00000008060	ENSLAFP00000006033	Frataxin.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.999
FXN	MRPL4	ENSLAFP00000008060	ENSLAFP00000012875	Frataxin.	Mitochondrial ribosomal protein L4.	0.497
FXN	SLC25A28	ENSLAFP00000008060	ENSLAFP00000004877	Frataxin.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.624
ISCU	ABCB7	ENSLAFP00000006033	ENSLAFP00000007382	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	ATP binding cassette subfamily B member 7.	0.723
ISCU	FXN	ENSLAFP00000006033	ENSLAFP00000008060	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Frataxin.	0.999
ISCU	MRPL4	ENSLAFP00000006033	ENSLAFP00000012875	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Mitochondrial ribosomal protein L4.	0.485
ISCU	RRP9	ENSLAFP00000006033	ENSLAFP00000004808	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.	0.511
ISCU	SLC25A28	ENSLAFP00000006033	ENSLAFP00000004877	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.616
METTL1	RRP9	ENSLAFP00000009030	ENSLAFP00000004808	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.	0.483
METTL1	SLC25A28	ENSLAFP00000009030	ENSLAFP00000004877	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.719
MRPL4	FXN	ENSLAFP00000012875	ENSLAFP00000008060	Mitochondrial ribosomal protein L4.	Frataxin.	0.497
MRPL4	ISCU	ENSLAFP00000012875	ENSLAFP00000006033	Mitochondrial ribosomal protein L4.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.485

page 1 of 2

Server load: low (12%) [HD]

Permalink

Network

Fusion

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

© STRING Consortium 2025

Credits

Access

Info

About