Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SLC25A28Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa)    
Predicted Functional Partners:
NARS2
Asparaginyl-tRNA synthetase 2, mitochondrial.
 
 
 
  0.912
SLC25A37
Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
 
 0.880
ABCB10
ATP binding cassette subfamily B member 10.
   
 
 0.799
METTL1
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
 
    0.720
FXN
Frataxin.
    
 
 0.695
ARIH1
RBR-type E3 ubiquitin transferase.
 
    
 0.676
SLC11A2
Solute carrier family 11 member 2.
   
  
 0.591
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
   
  
 0.564
ABCB8
ATP binding cassette subfamily B member 8.
   
 
 0.564
MTCH1
Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.537
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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