STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCY2CGuanylate cyclase. (1073 aa)    
Predicted Functional Partners:
GUCA2A
Guanylate cyclase activator 2A.
   
 0.994
GUCA2B
Guanylate cyclase activator 2B.
   
 0.984
PDE10A
Phosphodiesterase.
   
 0.966
PDE1B
Phosphodiesterase.
     
 0.963
NME1
Nucleoside diphosphate kinase.
     
 0.917
PDE5A
Phosphodiesterase.
   
 0.916
PDE6C
Phosphodiesterase.
   
 0.914
PDE1C
Phosphodiesterase.
     
 0.913
PDE1A
Phosphodiesterase.
     
 0.913
GCH1
GTP cyclohydrolase 1.
     
 0.906
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.