STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGD6FYVE, RhoGEF and PH domain containing 6. (1435 aa)    
Predicted Functional Partners:
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
      
 0.619
UHMK1
U2AF homology motif kinase 1.
      
 0.564
VAMP4
Vesicle associated membrane protein 4.
      
 0.536
GLRX
Glutaredoxin domain-containing protein.
    
 
 0.518
TMEM14A
Transmembrane protein 14A.
      
 0.516
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
     
 0.484
EGLN1
Fe2OG dioxygenase domain-containing protein.
      
 0.459
SNAP23
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
      
 0.456
ARHGEF16
Rho guanine nucleotide exchange factor 16.
   
  
 0.455
PPM1B
PPM-type phosphatase domain-containing protein.
      
 0.439
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.