SERINC2 protein (Loxodonta africana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SERINC2

Serine incorporator 2. (450 aa)

Predicted Functional Partners:

TTC14

0.626

GPN3

0.625

MPZL2

0.625

DOCK8

0.603

MOSPD2

0.571

ATP6V0A1

0.550

ICE2

0.535

ATP6V0A2

0.445

SERINC4

0.422

PIWIL4

0.417

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0A1	ATP6V0A2	ENSLAFP00000008900	ENSLAFP00000006145	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.996
ATP6V0A1	SERINC2	ENSLAFP00000008900	ENSLAFP00000004925	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Serine incorporator 2.	0.550
ATP6V0A2	ATP6V0A1	ENSLAFP00000006145	ENSLAFP00000008900	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.996
ATP6V0A2	SERINC2	ENSLAFP00000006145	ENSLAFP00000004925	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Serine incorporator 2.	0.445
DOCK8	SERINC2	ENSLAFP00000008899	ENSLAFP00000004925	Dedicator of cytokinesis 8; Belongs to the DOCK family.	Serine incorporator 2.	0.603
GPN3	MOSPD2	ENSLAFP00000005176	ENSLAFP00000008427	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	Motile sperm domain containing 2.	0.689
GPN3	MPZL2	ENSLAFP00000005176	ENSLAFP00000007119	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	Myelin protein zero like 2.	0.692
GPN3	SERINC2	ENSLAFP00000005176	ENSLAFP00000004925	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	Serine incorporator 2.	0.625
ICE2	SERINC2	ENSLAFP00000014789	ENSLAFP00000004925	Interactor of little elongation complex ELL subunit 2.	Serine incorporator 2.	0.535
MOSPD2	GPN3	ENSLAFP00000008427	ENSLAFP00000005176	Motile sperm domain containing 2.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.689
MOSPD2	MPZL2	ENSLAFP00000008427	ENSLAFP00000007119	Motile sperm domain containing 2.	Myelin protein zero like 2.	0.662
MOSPD2	SERINC2	ENSLAFP00000008427	ENSLAFP00000004925	Motile sperm domain containing 2.	Serine incorporator 2.	0.571
MPZL2	GPN3	ENSLAFP00000007119	ENSLAFP00000005176	Myelin protein zero like 2.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.692
MPZL2	MOSPD2	ENSLAFP00000007119	ENSLAFP00000008427	Myelin protein zero like 2.	Motile sperm domain containing 2.	0.662
MPZL2	SERINC2	ENSLAFP00000007119	ENSLAFP00000004925	Myelin protein zero like 2.	Serine incorporator 2.	0.625
PIWIL4	SERINC2	ENSLAFP00000007066	ENSLAFP00000004925	Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family.	Serine incorporator 2.	0.417
SERINC2	ATP6V0A1	ENSLAFP00000004925	ENSLAFP00000008900	Serine incorporator 2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.550
SERINC2	ATP6V0A2	ENSLAFP00000004925	ENSLAFP00000006145	Serine incorporator 2.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.445
SERINC2	DOCK8	ENSLAFP00000004925	ENSLAFP00000008899	Serine incorporator 2.	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.603
SERINC2	GPN3	ENSLAFP00000004925	ENSLAFP00000005176	Serine incorporator 2.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.625

page 1 of 2

Server load: low (14%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About