Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NID1Nidogen 1. (1245 aa)    
Predicted Functional Partners:
LAMC1
Laminin subunit gamma 1.
   
 0.982
NID2
Nidogen 2.
   
 0.972
HSPG2
Heparan sulfate proteoglycan 2.
   
 0.965
LAMB3
Laminin subunit beta 3.
   
 0.898
LAMA4
Laminin subunit alpha 4.
   
 0.847
FBLN1
Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
   
 0.833
LAMA3
Laminin subunit alpha 3.
   
 0.827
TNFAIP6
TNF alpha induced protein 6.
     
 0.805
MMP19
Matrix metallopeptidase 19.
   
 
 0.778
LAMC3
Laminin subunit gamma 3.
   
 0.762
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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