STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D5Rab-GAP TBC domain-containing protein. (462 aa)    
Predicted Functional Partners:
G3UHT2_LOXAF
Rab-GAP TBC domain-containing protein.
 
     0.931
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.728
G3UKG6_LOXAF
Metallophos_2 domain-containing protein.
    
 
 0.728
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.727
VPS26A
VPS26, retromer complex component A.
   
 
 0.697
VPS26B
VPS26, retromer complex component B.
   
 
 0.691
PEX3
Peroxisomal biogenesis factor 3.
      
 0.509
RAB6B
RAB6B, member RAS oncogene family.
   
 
 0.492
RAB6A
RAB6A, member RAS oncogene family.
   
 
 0.492
SNX27
Sorting nexin 27.
    
 
 0.468
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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