Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CREBL2cAMP responsive element binding protein like 2. (170 aa)    
Predicted Functional Partners:
CREBRF
CREB3 regulatory factor.
   
 
 0.769
THOC7
THO complex 7.
    
   0.665
KCNK6
Potassium two pore domain channel subfamily K member 6; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.588
CRTC3
CREB regulated transcription coactivator 3.
      
 0.549
BORCS6
BLOC-1 related complex subunit 6.
   
 
 0.547
SNAPIN
SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]
   
 
 0.530
BORCS8
Uncharacterized protein.
    
 
 0.526
APBA2
Amyloid beta precursor protein binding family A member 2.
      
 0.508
KLHL15
Kelch like family member 15.
      
 0.502
ETV6
ETS variant 6.
      
 0.502
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.