Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGR3Anterior gradient 3, protein disulphide isomerase family member. (166 aa)    
Predicted Functional Partners:
AGR2
Anterior gradient 2, protein disulphide isomerase family member.
   
    0.928
BRICD5
BRICHOS domain containing 5.
      
 0.737
ERP29
Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase.
      
 0.676
LYPD3
LY6/PLAUR domain containing 3.
    
 
 0.675
ZPLD1
Zona pellucida like domain containing 1.
      
 0.653
TMX1
Thioredoxin related transmembrane protein 1.
      
 0.627
CIB3
Calcium and integrin binding family member 3.
      
 0.627
ERP44
Endoplasmic reticulum protein 44.
      
 0.568
PDIA5
Protein disulfide isomerase family A member 5.
      
 0.560
PDIA3
Protein disulfide-isomerase.
      
 0.526
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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