Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TEX264Testis expressed 264, ER-phagy receptor. (312 aa)    
Predicted Functional Partners:
TMEM79
Transmembrane protein 79.
    
   0.794
SEC62
SEC62 homolog, preprotein translocation factor.
      
 0.634
CCPG1
Cell cycle progression 1.
     
 0.611
G3UC47_LOXAF
Uncharacterized protein.
     
 0.611
ETHE1
ETHE1 persulfide dioxygenase.
      
 0.594
ATL3
Atlastin GTPase 3.
      
 0.593
ZNF428
Zinc finger protein 428.
      
 0.588
MAS1
MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.557
MED20
Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.552
RETREG1
Reticulophagy regulator 1.
      
 0.548
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (12%) [HD]