RNF169 protein (Loxodonta africana) - STRING interaction network

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RNF169

Ring finger protein 169. (471 aa)

Predicted Functional Partners:

DYRK1A

0.956

DCAF7

0.870

USP7

0.840

UBA52

0.834

FBXO38

0.818

RPS27A

0.760

G3U9C8_LOXAF

0.760

DYRK1B

0.754

BRCA1

0.748

UBB

0.747

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA1	G3U9C8_LOXAF	ENSLAFP00000012177	ENSLAFP00000024436	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ubiquitin-like domain-containing protein.	0.554
BRCA1	RNF169	ENSLAFP00000012177	ENSLAFP00000005022	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ring finger protein 169.	0.748
BRCA1	RPS27A	ENSLAFP00000012177	ENSLAFP00000021261	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ubiquitin-like domain-containing protein.	0.554
BRCA1	UBB	ENSLAFP00000012177	ENSLAFP00000025209	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Ubiquitin B.	0.739
DCAF7	DYRK1A	ENSLAFP00000008543	ENSLAFP00000000681	DDB1 and CUL4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 1A.	0.968
DCAF7	DYRK1B	ENSLAFP00000008543	ENSLAFP00000023479	DDB1 and CUL4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 1B.	0.963
DCAF7	RNF169	ENSLAFP00000008543	ENSLAFP00000005022	DDB1 and CUL4 associated factor 7.	Ring finger protein 169.	0.870
DYRK1A	DCAF7	ENSLAFP00000000681	ENSLAFP00000008543	Dual specificity tyrosine phosphorylation regulated kinase 1A.	DDB1 and CUL4 associated factor 7.	0.968
DYRK1A	DYRK1B	ENSLAFP00000000681	ENSLAFP00000023479	Dual specificity tyrosine phosphorylation regulated kinase 1A.	Dual specificity tyrosine phosphorylation regulated kinase 1B.	0.884
DYRK1A	RNF169	ENSLAFP00000000681	ENSLAFP00000005022	Dual specificity tyrosine phosphorylation regulated kinase 1A.	Ring finger protein 169.	0.956
DYRK1B	DCAF7	ENSLAFP00000023479	ENSLAFP00000008543	Dual specificity tyrosine phosphorylation regulated kinase 1B.	DDB1 and CUL4 associated factor 7.	0.963
DYRK1B	DYRK1A	ENSLAFP00000023479	ENSLAFP00000000681	Dual specificity tyrosine phosphorylation regulated kinase 1B.	Dual specificity tyrosine phosphorylation regulated kinase 1A.	0.884
DYRK1B	RNF169	ENSLAFP00000023479	ENSLAFP00000005022	Dual specificity tyrosine phosphorylation regulated kinase 1B.	Ring finger protein 169.	0.754
FBXO38	RNF169	ENSLAFP00000012066	ENSLAFP00000005022	F-box protein 38.	Ring finger protein 169.	0.818
FBXO38	USP7	ENSLAFP00000012066	ENSLAFP00000006345	F-box protein 38.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.860
G3U9C8_LOXAF	BRCA1	ENSLAFP00000024436	ENSLAFP00000012177	Ubiquitin-like domain-containing protein.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.554
G3U9C8_LOXAF	RNF169	ENSLAFP00000024436	ENSLAFP00000005022	Ubiquitin-like domain-containing protein.	Ring finger protein 169.	0.760
G3U9C8_LOXAF	UBA52	ENSLAFP00000024436	ENSLAFP00000017811	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.995
G3U9C8_LOXAF	UBB	ENSLAFP00000024436	ENSLAFP00000025209	Ubiquitin-like domain-containing protein.	Ubiquitin B.	0.935
G3U9C8_LOXAF	USP7	ENSLAFP00000024436	ENSLAFP00000006345	Ubiquitin-like domain-containing protein.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.848

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