STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP1LDL receptor related protein 1. (4490 aa)    
Predicted Functional Partners:
APOE
Apolipoprotein E.
    
 0.949
LRPAP1
LDL receptor related protein associated protein 1.
    
 0.941
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
    
 0.925
LRP2
LDL receptor related protein 2.
     
0.907
PCSK9
Proprotein convertase subtilisin/kexin type 9.
    
 0.761
AGRN
Agrin.
    
 0.635
DKK1
Dickkopf-like protein 1.
    
 0.608
ITSN2
Intersectin 2.
    
 0.604
G3U095_LOXAF
Uncharacterized protein.
    
 0.604
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.578
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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