Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F5E2F transcription factor 5. (343 aa)    
Predicted Functional Partners:
RBL2
RB transcriptional corepressor like 2.
   
 0.988
TFDP1
Transcription factor.
   
 0.982
TFDP2
Transcription factor.
   
 0.981
RB1
RB transcriptional corepressor 1.
   
 0.981
RBL1
RB transcriptional corepressor like 1.
   
 0.978
E2F4
E2F transcription factor 4.
   
 0.961
LIN9
Lin-9 DREAM MuvB core complex component.
    
 0.941
LIN37
Lin-37 DREAM MuvB core complex component.
    
 0.938
SMAD4
Mothers against decapentaplegic homolog.
    
 0.926
E2F2
E2F transcription factor 2.
  
 
0.919
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.