STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (576 aa)    
Predicted Functional Partners:
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.880
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.850
USP14
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 
 0.840
UBB
Ubiquitin B.
   
 0.808
UBC
Uncharacterized protein.
   
 0.808
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.761
G3U9C8_LOXAF
Ubiquitin-like domain-containing protein.
    
 0.761
OTUB1
Ubiquitin thioesterase.
   
 0.757
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.743
MDM4
Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.
   
 0.702
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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