STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL21Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)    
Predicted Functional Partners:
IL2RG
Fibronectin type-III domain-containing protein.
   
 0.978
IL21R
Interleukin 21 receptor.
  
 0.963
JAK3
Tyrosine-protein kinase.
   
 
 0.954
JAK1
Tyrosine-protein kinase.
   
 
 0.954
IL4R
Interleukin 4 receptor.
  
  
 0.812
IL22RA1
Interleukin 22 receptor subunit alpha 1.
  
  
 0.745
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
  
   
 0.698
STAT3
Signal transducer and activator of transcription.
   
 
 0.697
IFNAR1
Interferon alpha and beta receptor subunit 1.
     
 0.694
IL12RB2
Interleukin 12 receptor subunit beta 2.
   
 
 0.691
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.