STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BIRC3Baculoviral IAP repeat containing 3. (603 aa)    
Predicted Functional Partners:
TNFRSF1A
TNF receptor superfamily member 1A.
    
 0.966
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.965
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 0.954
TRADD
TNFRSF1A associated via death domain.
   
 0.953
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.953
CASP3
Caspase 3; Belongs to the peptidase C14A family.
   
 0.953
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.948
CASP7
Caspase 7; Belongs to the peptidase C14A family.
   
 0.947
HTRA2
HtrA serine peptidase 2.
    
 0.945
RNF31
Uncharacterized protein.
    
 0.941
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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