STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TICRRTOPBP1 interacting checkpoint and replication regulator. (1880 aa)    
Predicted Functional Partners:
CDC45
Cell division cycle 45.
   
  
 0.793
G3T376_LOXAF
Uncharacterized protein.
    
 
 0.744
TOPBP1
BRCT domain-containing protein.
    
 
 0.744
EXO1
Exonuclease 1.
  
 
 0.735
DBF4
DBF4 zinc finger.
   
  
 0.732
MTBP
MDM2 binding protein.
   
 0.730
MCM10
Minichromosome maintenance 10 replication initiation factor.
   
  
 0.711
RECQL4
RecQ like helicase 4.
  
 
 0.695
TBL3
Transducin beta like 3.
   
 
 0.684
WDR36
WD repeat domain 36.
   
 
 0.669
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.