Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM13AUncharacterized protein. (180 aa)    
Predicted Functional Partners:
MYPN
Myopalladin.
     
 0.753
FAM184B
Family with sequence similarity 184 member B.
      
 0.737
SIRT1
Sirtuin 1.
      
 0.638
HERC3
HECT domain-containing protein.
      
 0.625
FAM43B
Family with sequence similarity 43 member B.
      
 0.566
HHIP
Hedgehog interacting protein.
    
 
 0.556
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5.
      
 0.546
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4.
      
 0.545
IREB2
Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
    
 
 0.531
OGFOD2
2-oxoglutarate and iron dependent oxygenase domain containing 2.
    
 
 0.524
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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