PRSS48 protein (Loxodonta africana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PRSS48

Serine protease 48; Belongs to the peptidase S1 family. (270 aa)

Predicted Functional Partners:

GLYATL3

0.550

CA10

0.420

SCAF11

0.420

G3U2E5_LOXAF

0.420

SH3D19

0.416

LYAR

0.413

NOS1AP

0.413

BCCIP

0.411

EXOSC4

0.411

TRIM68

0.405

Your Current Organism:

Loxodonta africana

NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCCIP	EXOSC4	ENSLAFP00000018043	ENSLAFP00000018610	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Exosome component 4.	0.466
BCCIP	GLYATL3	ENSLAFP00000018043	ENSLAFP00000023841	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Glycine-N-acyltransferase like 3.	0.414
BCCIP	LYAR	ENSLAFP00000018043	ENSLAFP00000013921	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Ly1 antibody reactive.	0.728
BCCIP	PRSS48	ENSLAFP00000018043	ENSLAFP00000005174	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Serine protease 48; Belongs to the peptidase S1 family.	0.411
CA10	PRSS48	ENSLAFP00000013325	ENSLAFP00000005174	Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family.	Serine protease 48; Belongs to the peptidase S1 family.	0.420
EXOSC4	BCCIP	ENSLAFP00000018610	ENSLAFP00000018043	Exosome component 4.	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	0.466
EXOSC4	GLYATL3	ENSLAFP00000018610	ENSLAFP00000023841	Exosome component 4.	Glycine-N-acyltransferase like 3.	0.413
EXOSC4	LYAR	ENSLAFP00000018610	ENSLAFP00000013921	Exosome component 4.	Ly1 antibody reactive.	0.473
EXOSC4	PRSS48	ENSLAFP00000018610	ENSLAFP00000005174	Exosome component 4.	Serine protease 48; Belongs to the peptidase S1 family.	0.411
G3U2E5_LOXAF	GLYATL3	ENSLAFP00000022003	ENSLAFP00000023841	Uncharacterized protein.	Glycine-N-acyltransferase like 3.	0.418
G3U2E5_LOXAF	PRSS48	ENSLAFP00000022003	ENSLAFP00000005174	Uncharacterized protein.	Serine protease 48; Belongs to the peptidase S1 family.	0.420
GLYATL3	BCCIP	ENSLAFP00000023841	ENSLAFP00000018043	Glycine-N-acyltransferase like 3.	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	0.414
GLYATL3	EXOSC4	ENSLAFP00000023841	ENSLAFP00000018610	Glycine-N-acyltransferase like 3.	Exosome component 4.	0.413
GLYATL3	G3U2E5_LOXAF	ENSLAFP00000023841	ENSLAFP00000022003	Glycine-N-acyltransferase like 3.	Uncharacterized protein.	0.418
GLYATL3	LYAR	ENSLAFP00000023841	ENSLAFP00000013921	Glycine-N-acyltransferase like 3.	Ly1 antibody reactive.	0.417
GLYATL3	PRSS48	ENSLAFP00000023841	ENSLAFP00000005174	Glycine-N-acyltransferase like 3.	Serine protease 48; Belongs to the peptidase S1 family.	0.550
GLYATL3	SCAF11	ENSLAFP00000023841	ENSLAFP00000017813	Glycine-N-acyltransferase like 3.	RING-type domain-containing protein.	0.418
LYAR	BCCIP	ENSLAFP00000013921	ENSLAFP00000018043	Ly1 antibody reactive.	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	0.728
LYAR	EXOSC4	ENSLAFP00000013921	ENSLAFP00000018610	Ly1 antibody reactive.	Exosome component 4.	0.473
LYAR	GLYATL3	ENSLAFP00000013921	ENSLAFP00000023841	Ly1 antibody reactive.	Glycine-N-acyltransferase like 3.	0.417

page 1 of 2

Server load: low (28%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About