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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (406 aa)    
Predicted Functional Partners:
RAD1
RAD1 checkpoint DNA exonuclease.
    
 0.995
HUS1
Checkpoint protein; Belongs to the HUS1 family.
    
 0.991
WRN
WRN RecQ like helicase.
   
 0.980
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.975
RAD17
RAD17 checkpoint clamp loader component.
   
 0.956
RFC2
Replication factor C subunit 2.
   
 0.945
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
  
  
 
0.941
RFC4
Replication factor C subunit 4.
   
 0.927
RFC3
Replication factor C subunit 3.
   
 0.906
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.840
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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