STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TDRKHTudor and KH domain containing. (559 aa)    
Predicted Functional Partners:
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 0.925
PIWIL4
Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family.
   
 0.828
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
   
 0.828
CLNS1A
Chloride nucleotide-sensitive channel 1A.
      
 0.756
FKBP6
Peptidylprolyl isomerase.
     
 0.748
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...]
   
 0.725
PNLDC1
PARN like, ribonuclease domain containing 1.
      
 0.715
TDRD9
Tudor domain containing 9.
    
 0.695
MAEL
Maelstrom spermatogenic transposon silencer.
     
 0.691
HENMT1
HEN methyltransferase 1.
     
 0.687
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.