STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDRKHTudor and KH domain containing. (559 aa)    
Predicted Functional Partners:
PIWIL4
Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family.
   
 0.809
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
   
 0.800
PNLDC1
PARN like, ribonuclease domain containing 1.
      
 0.799
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 0.766
FKBP6
Peptidylprolyl isomerase.
     
 0.717
SND1
Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.
   
0.627
EXD1
Exonuclease 3'-5' domain containing 1.
      
 0.607
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...]
   
 0.606
TDRD9
Tudor domain containing 9.
    
0.596
PLD6
PLD phosphodiesterase domain-containing protein.
    
 
 0.595
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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