STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HENMT1HEN methyltransferase 1. (342 aa)    
Predicted Functional Partners:
DICER1
Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.
   
 
 0.680
PLD6
PLD phosphodiesterase domain-containing protein.
      
 0.667
TDRD9
Tudor domain containing 9.
     
 0.606
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...]
     
 0.587
SPEM1
Spermatid maturation 1.
      
 0.573
TDRKH
Tudor and KH domain containing.
     
 0.568
FKBP6
Peptidylprolyl isomerase.
      
 0.546
G3SY39_LOXAF
Uncharacterized protein.
     
 0.475
ICE2
Interactor of little elongation complex ELL subunit 2.
    
 
 0.465
YTHDC2
YTH domain containing 2.
     
 0.460
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.