Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UPK1ATetraspanin. (257 aa)    
Predicted Functional Partners:
UPK2
Uroplakin 2.
  
 
 0.980
UPK3A
Uroplakin 3A.
   
 
 0.887
UPK3B
Uroplakin 3B.
   
  
 0.740
TSPAN31
Tetraspanin 31; Belongs to the tetraspanin (TM4SF) family.
      
 0.665
RBP5
Retinol binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.617
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 0.490
CD53
Tetraspanin.
      
 0.485
CD37
Tetraspanin.
      
 0.455
SNN
Stannin.
  
     0.443
ARHGAP27
Rho GTPase activating protein 27.
   
  
 0.442
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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