Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM210AFamily with sequence similarity 210 member A. (273 aa)    
Predicted Functional Partners:
HIBADH
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
   
  
 0.603
ATAD3A
ATPase family AAA domain containing 3A.
    
 
 0.594
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
     
  0.524
SSR3
Signal sequence receptor subunit 3.
     
  0.524
GFM1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]
   
    0.519
C15orf40
Chromosome 15 open reading frame 40.
   
  
 0.513
DDX27
DEAD-box helicase 27; Belongs to the DEAD box helicase family.
      
 0.504
PTPN18
Protein tyrosine phosphatase non-receptor type 18.
      
 0.477
GINS3
GINS complex subunit 3.
   
  
 0.442
IQCA1
IQ motif containing with AAA domain 1.
   
  
 0.427
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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