STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCY2DGuanylate cyclase. (949 aa)    
Predicted Functional Partners:
GUCA1B
Guanylate cyclase activator 1B.
   
 0.938
GUCA1A
Uncharacterized protein.
   
 0.915
NUDT2
Nudix hydrolase 2.
     
  0.851
PDE2A
Phosphodiesterase.
   
 0.821
PDE6C
Phosphodiesterase.
   
 0.815
NME4
NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family.
     
 0.807
NME6
Nucleoside diphosphate kinase.
     
 0.807
ENTPD1
Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.
   
 
  0.805
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
   
 
  0.805
PDE3A
Phosphodiesterase.
   
 0.803
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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