STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPCAMEpithelial cell adhesion molecule. (315 aa)    
Predicted Functional Partners:
CD44
CD44 molecule (Indian blood group).
      
 0.743
CD24
Uncharacterized protein.
   
  
 0.670
EGFR
Receptor protein-tyrosine kinase.
   
  
 0.588
ERBB2
Receptor protein-tyrosine kinase.
   
  
 0.583
CD9
Tetraspanin.
      
 0.583
MUC1
SEA domain-containing protein.
   
  
 0.572
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.544
KRT19
Keratin 19; Belongs to the intermediate filament family.
   
  
 0.532
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.519
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
   
  
 0.519
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.