STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTM1Myotubularin 1. (603 aa)    
Predicted Functional Partners:
FIG4
FIG4 phosphoinositide 5-phosphatase.
     
 0.934
SACM1L
SAC1 like phosphatidylinositide phosphatase.
   
 
 0.922
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.920
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
     
 0.915
INPP4B
Inositol polyphosphate-4-phosphatase type II B.
   
 
 0.914
PIP4P1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
 
   
 0.910
IMPAD1
Inositol monophosphatase domain containing 1.
    
 0.909
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.908
IMPA1
Inositol-1-monophosphatase.
     
 0.908
PLCD1
Phosphoinositide phospholipase C.
     
 0.907
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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