Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA3Pleckstrin homology domain containing A3. (299 aa)    
Predicted Functional Partners:
GLTP
Glycolipid transfer protein.
      
 0.666
CFAP65
Cilia and flagella associated protein 65.
      
 0.652
CEL
Carboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family.
      
 0.644
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
   
    0.596
PLEKHA8
Pleckstrin homology domain containing A8.
    
  0.587
PLEKHA2
Pleckstrin homology domain containing A2.
      
 0.546
MNAT1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
      
 0.539
PLEK2
Pleckstrin 2.
      
 0.512
CDC37L1
Cell division cycle 37 like 1.
      
 0.507
ENPP5
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5.
      
 0.504
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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