STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGI1Leucine rich glioma inactivated 1. (557 aa)    
Predicted Functional Partners:
ADAM11
ADAM metallopeptidase domain 11.
     
 0.844
ADAM23
ADAM metallopeptidase domain 23.
     
 0.660
ADAM22
ADAM metallopeptidase domain 22.
     
 0.653
GRIN1
ANF_receptor domain-containing protein.
   
  
 0.576
ZDBF2
Zinc finger DBF-type containing 2.
     
 0.535
EFHC1
EF-hand domain containing 1.
      
 0.490
SPNS2
Sphingolipid transporter 2.
      
 0.461
NXPH1
Neurexophilin; May be signaling molecules that resemble neuropeptides.
  
    0.424
NXPH2
Neurexophilin; May be signaling molecules that resemble neuropeptides.
  
    0.405
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.