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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (850 aa)    
Predicted Functional Partners:
G3UGB1_LOXAF
GON domain-containing protein.
 
   
 0.898
ACAN
Aggrecan.
     
 0.848
BCAN
Brevican.
     
 0.844
MMP13
Matrix metallopeptidase 13.
   
 
 0.673
COL2A1
Collagen type II alpha 1 chain.
    
 0.469
MMP9
Matrix metallopeptidase 9.
    
 
 0.450
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 
 0.433
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 
 0.422
OSM
Oncostatin M.
      
 0.420
COL1A1
Collagen type I alpha 1 chain.
    
 0.419
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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